Samuel Isaly is Managing Partner and Founder of Exome Asset Management. Mr. Isaly is an experienced healthcare fund manager and has been active in global healthcare investing and analysis for over 45 years.

Over the course of his career, Sam Isaly has been a pharmaceutical analyst with Chase Manhattan Bank, Merrill Lynch, Legg Mason, and S.G. Warburg. In 1989, Mr. Isaly launched OrbiMed Advisors LLC. During his time at OrbiMed, Mr. Isaly was the portfolio manager of Worldwide Healthcare Trust Plc for 22 years.

Mr. Isaly received an A.B. in Economics from Princeton University from which he graduated magna cum laude. Sam was awarded the Percy Allen Ransome Sr. Prize in Economics and was a recipient of the Lieutenant John A. Larkin, Jr., Memorial Scholarship. He was a Fulbright Scholar and attended The London School of Economics where he earned a M. Sc. (Econ.).